Author: Leaker, Brian R.; Singh, Dave; Lindgren, Sam; Almqvist, Gun; Eriksson, Leif; Young, Barbara; O’Connor, Brian
Title: Effects of the Toll-like receptor 7 (TLR7) agonist, AZD8848, on allergen-induced responses in patients with mild asthma: a double-blind, randomised, parallel-group study Document date: 2019_12_19
ID: 15e043uf_34
Snippet: The average EAR fall in FEV 1 was numerically reduced by 18% with AZD8848 versus placebo at 1 week after the last dose, but this did not reach statistical significance (p = 0.28; Fig. 4a ). No effect was demonstrated on the repeat allergen challenge 4 weeks post-treatment (Fig. 4b) ......
Document: The average EAR fall in FEV 1 was numerically reduced by 18% with AZD8848 versus placebo at 1 week after the last dose, but this did not reach statistical significance (p = 0.28; Fig. 4a ). No effect was demonstrated on the repeat allergen challenge 4 weeks post-treatment (Fig. 4b) .
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