Author: Mohd Ropidi, Muhammad Izzuddin; Khazali, Ahmad Suhail; Nor Rashid, Nurshamimi; Yusof, Rohana
Title: Endoplasmic reticulum: a focal point of Zika virus infection Document date: 2020_1_20
ID: 0zr2e8lh_19
Snippet: In summary, ZIKV and several ZIKV proteins localize to the ER and eventually leads to the remodeling of the reticular architecture and exploitation of the organelle's unique characteristics. These modifications create an ideal environment for viral genome replication, but simultaneously introduce additional burden and stress on the host cell leading to the activation of several cellular responses, which will be discussed in the following sections.....
Document: In summary, ZIKV and several ZIKV proteins localize to the ER and eventually leads to the remodeling of the reticular architecture and exploitation of the organelle's unique characteristics. These modifications create an ideal environment for viral genome replication, but simultaneously introduce additional burden and stress on the host cell leading to the activation of several cellular responses, which will be discussed in the following sections.
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