Author: De Jong, Cornelis N.; Saes, Lotte; Klerk, Clara P. W.; Van der Klift, Marjolein; Cornelissen, Jan J.; Broers, Annoek E. C.
Title: Etanercept for steroid-refractory acute graft-versus-host disease: A single center experience Document date: 2017_10_26
ID: 1hcp36cw_26
Snippet: Acute GVHD is an important cause of morbidity and mortality following alloSCT. Steroidrefractory acute GVHD in particular is associated with a poor prognosis with a long term overall survival of only 20-30%. Studies evaluating second-line treatment with the anti-TFNα agent etanercept have shown promising results with overall response rates of 50-80% [8] [9] [10] ......
Document: Acute GVHD is an important cause of morbidity and mortality following alloSCT. Steroidrefractory acute GVHD in particular is associated with a poor prognosis with a long term overall survival of only 20-30%. Studies evaluating second-line treatment with the anti-TFNα agent etanercept have shown promising results with overall response rates of 50-80% [8] [9] [10] .
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