Author: Laneve, Pietro; Piacentini, Lucia; Casale, Assunta Maria; Capauto, Davide; Gioia, Ubaldo; Cappucci, Ugo; Di Carlo, Valerio; Bozzoni, Irene; Di Micco, Patrizio; Morea, Veronica; Di Franco, Carmela Antonia; Caffarelli, Elisa
Title: Drosophila CG3303 is an essential endoribonuclease linked to TDP-43-mediated neurodegeneration Document date: 2017_1_31
ID: 1rw05x6m_1
Snippet: Sequence and structure analyses of Drosophila XendoU homologs. Sequence analysis highlighted the occurrence of two Drosophila proteins homologous to X. laevis XendoU, encoded by CG2145 and CG3303 genes (www.flybase.org). The CG2145 product is assigned an endoribonuclease activity, whereas the CG3303 product is annotated as putative serine-protease by the UniProt (http://www.uniprot.org/), NCBI (www.ncbi.nlm. nih.gov) and GO (http://gowiki.tamu.ed.....
Document: Sequence and structure analyses of Drosophila XendoU homologs. Sequence analysis highlighted the occurrence of two Drosophila proteins homologous to X. laevis XendoU, encoded by CG2145 and CG3303 genes (www.flybase.org). The CG2145 product is assigned an endoribonuclease activity, whereas the CG3303 product is annotated as putative serine-protease by the UniProt (http://www.uniprot.org/), NCBI (www.ncbi.nlm. nih.gov) and GO (http://gowiki.tamu.edu/wiki/index.php/Main_Page) databases.
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