Author: Murdaca, Giuseppe; Tonacci, Alessandro; Negrini, Simone; Greco, Monica; Borro, Matteo; Puppo, Francesco; Gangemi, Sebastiano
Title: Effects of AntagomiRs on Different Lung Diseases in Human, Cellular, and Animal Models Document date: 2019_8_13
ID: 1rmwwjgi_11
Snippet: Under this category, studies dealing with asthma, COPD, allergic airway disease, airway hyper-responsiveness were included. Overall, eight studies were found, the majority of which investigating COPD (four studies) or asthma (three articles). Despite the heterogeneity in terms of miRNAs investigated, in this case promoted by both the relatively low number of studies retrieved and by the slightly different kind of diseases included in this categor.....
Document: Under this category, studies dealing with asthma, COPD, allergic airway disease, airway hyper-responsiveness were included. Overall, eight studies were found, the majority of which investigating COPD (four studies) or asthma (three articles). Despite the heterogeneity in terms of miRNAs investigated, in this case promoted by both the relatively low number of studies retrieved and by the slightly different kind of diseases included in this category, miR-21 was included in several studies and its activity successfully challenged by its corresponding antagomiR. In summary, despite the differences in terms of category of samples studied and antagomiRs used, these compounds have demonstrated their usefulness also in this class of clinical conditions.
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