Selected article for: "fiber gene and hexon gene"
Author: Lu, Qing-Bin; Tong, Yi-Gang; Wo, Ying; Wang, Hong-Yu; Liu, En-Mei; Gray, Gregory C; Liu, Wei; Cao, Wu-Chun
Title: Epidemiology of human adenovirus and molecular characterization of human adenovirus 55 in China, 2009–2012
  • Document date: 2014_1_28
    • ID: 0jb8vgt9_27
    Snippet: Recombination is a well-known feature in HAdV genetics and an important force driving the evolution of HAdV. 1, 2 Our study further supported the hypothesis that HAdV-55 is a recombinant between HAdV-11 and HAdV-14 strains and more HAdV-14-like than HAdV-11-like. 5 Meanwhile, Based on the phylogenetic trees for hexon gene, the Singapore strains are more closely related to the mainland China HAdV-55 strains than with Taiwan strains while the oppos.....
    Document: Recombination is a well-known feature in HAdV genetics and an important force driving the evolution of HAdV. 1, 2 Our study further supported the hypothesis that HAdV-55 is a recombinant between HAdV-11 and HAdV-14 strains and more HAdV-14-like than HAdV-11-like. 5 Meanwhile, Based on the phylogenetic trees for hexon gene, the Singapore strains are more closely related to the mainland China HAdV-55 strains than with Taiwan strains while the opposite to the fiber gene. These results suggested a possible recombination event occurred at a position between hexon gene and fiber gene, between mainland China strain and Taiwan strain, which resulted in the formation of the Singapore strain. All the strains in mainland of China seem to be different from other regional HAdV-55 strains. These characteristics might reflect either spatial or temporal dynamics of HAdV-55.

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