Selected article for: "accurate diagnostic and genome sequence"

Author: Chantal B.F. Vogels; Anderson F. Brito; Anne Louise Wyllie; Joseph R Fauver; Isabel M. Ott; Chaney C. Kalinich; Mary E. Petrone; Marie-Louise Landry; Ellen F. Foxman; Nathan D. Grubaugh
Title: Analytical sensitivity and efficiency comparisons of SARS-COV-2 qRT-PCR assays
  • Document date: 2020_4_1
  • ID: 6mdimxnk_1
    Snippet: Accurate diagnostic assays and large-scale testing are critical for mitigating outbreaks of infectious diseases. Early detection prompts public health actions to prevent and control the spread of pathogens. This has been exemplified by the novel coronavirus, known as SARS-CoV-2, which was first identified as the cause of an outbreak of pneumonia in Wuhan, China, in December 2019, and rapidly spread around the world 1-3 . The first SARS-CoV-2 geno.....
    Document: Accurate diagnostic assays and large-scale testing are critical for mitigating outbreaks of infectious diseases. Early detection prompts public health actions to prevent and control the spread of pathogens. This has been exemplified by the novel coronavirus, known as SARS-CoV-2, which was first identified as the cause of an outbreak of pneumonia in Wuhan, China, in December 2019, and rapidly spread around the world 1-3 . The first SARS-CoV-2 genome sequence was critical for the development of diagnostics 2 , which led to several molecular assays being developed to detect COVID-19 cases [4] [5] [6] [7] . The World Health Organization (WHO) currently lists seven molecular assays (i.e. qRT-PCR) to diagnose COVID-19 8 ; however, it is not clear to many laboratories or public health agencies which assay they should adopt.

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