Evaluation of the efficacy of a trivalent vaccine mixture against a triple challenge with Mycoplasma hyopneumoniae, PCV2, and PRRSV and the efficacy comparison of the respective monovalent vaccines against a single challenge

Oh, Taehwan; Park, Kee Hwan; Yang, Siyeon; Jeong, Jiwoon; Kang, Ikjae; Park, Changhoon; Chae, Chanhee

The Vac3FLEX/Ch3 and VacPRRS/ChPRRSV groups had a significantly lower (P < 0.05) number of genomic copies of PRRSV in their blood compared to the UnVac/Ch3 and UnVac/ChPRRSV groups at − 7, 0, 7, and 14 dpc. The VacPRRS/ChPRRSV group had a significantly lower (P < 0.05) number of genomic copies of PRRSV in their blood compared to the UnVac/Ch3 group at 28 dpc. The UnVac/ChPRRSV group had a significantly lower (P < 0.05) number of genomic copies of PRRSV in their blood compared to the UnVac/Ch3 group at 0 dpc. No genomic copies of PRRSV were detected in any of the pigs from UnVac/UnCh group (Fig. 2c) . No genomic copies of M. hyopneumoniae, PCV2, and PRRSV were detected in any of the pigs from the UnVac/UnCh group.