Selected article for: "amino acid and envelope gene"

Author: Drexler, Jan Felix; Corman, Victor Max; Müller, Marcel Alexander; Lukashev, Alexander N.; Gmyl, Anatoly; Coutard, Bruno; Adam, Alexander; Ritz, Daniel; Leijten, Lonneke M.; van Riel, Debby; Kallies, Rene; Klose, Stefan M.; Gloza-Rausch, Florian; Binger, Tabea; Annan, Augustina; Adu-Sarkodie, Yaw; Oppong, Samuel; Bourgarel, Mathieu; Rupp, Daniel; Hoffmann, Bernd; Schlegel, Mathias; Kümmerer, Beate M.; Krüger, Detlev H.; Schmidt-Chanasit, Jonas; Setién, Alvaro Aguilar; Cottontail, Veronika M.; Hemachudha, Thiravat; Wacharapluesadee, Supaporn; Osterrieder, Klaus; Bartenschlager, Ralf; Matthee, Sonja; Beer, Martin; Kuiken, Thijs; Reusken, Chantal; Leroy, Eric M.; Ulrich, Rainer G.; Drosten, Christian
Title: Evidence for Novel Hepaciviruses in Rodents
  • Document date: 2013_6_20
  • ID: 1v353uij_41
    Snippet: The total amino acid diversity of all homologous genes within the polyproteins of the three rodent hepacivirus clades was larger than that of all HCV genotypes (Supplementary Table S4 ). Similar to HCV, the most variable genomic regions in rodent hepaciviruses were located in the Envelope E2 gene differing in up to 84.4% of encoded amino acids between the rodent virus clades; the NS2 gene differing in up to 79.8%; and the NS5A gene differing by u.....
    Document: The total amino acid diversity of all homologous genes within the polyproteins of the three rodent hepacivirus clades was larger than that of all HCV genotypes (Supplementary Table S4 ). Similar to HCV, the most variable genomic regions in rodent hepaciviruses were located in the Envelope E2 gene differing in up to 84.4% of encoded amino acids between the rodent virus clades; the NS2 gene differing in up to 79.8%; and the NS5A gene differing by up to 84.6%.

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