Selected article for: "cell type and infected cell"

Author: Mohd Ropidi, Muhammad Izzuddin; Khazali, Ahmad Suhail; Nor Rashid, Nurshamimi; Yusof, Rohana
Title: Endoplasmic reticulum: a focal point of Zika virus infection
  • Document date: 2020_1_20
  • ID: 0zr2e8lh_13
    Snippet: ZIKV infection also forms distinct aggregates of intricate ER tubular network that resembles sponge-like matrix called the convoluted membranes (CM) (Fig. 1 ) [32, [35] [36] [37] . CM aggregates are frequently seen bordering ZIKV virions and other ZIKV-induced structures, with occasional virions also found within the CM itself [32, 36] . The function of the CM in ZIKV infection is unclear; nevertheless, evidence from other flaviviruses studies su.....
    Document: ZIKV infection also forms distinct aggregates of intricate ER tubular network that resembles sponge-like matrix called the convoluted membranes (CM) (Fig. 1 ) [32, [35] [36] [37] . CM aggregates are frequently seen bordering ZIKV virions and other ZIKV-induced structures, with occasional virions also found within the CM itself [32, 36] . The function of the CM in ZIKV infection is unclear; nevertheless, evidence from other flaviviruses studies suggest that the CM possesses roles closely associated to protein synthesis and processing [18] . Interestingly, CM aggregates are not observed in ZIKV-infected neural progenitor cells, suggesting cell-type-specific factors are required to develop the CM [32] . No discernible difference in the CM structure is observed between the African and Asian ZIKV strains [36, 37] .

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