Expanding severe acute respiratory infection (SARI) surveillance beyond influenza: The process and data from 1 year of implementation in Vietnam

Alroy, Karen A.; Do, Trang Thuy; Tran, Phu Dac; Dang, Tan Quang; Vu, Long Ngoc; Le, Nga Thi Hang; Dang, Anh Duc; Ngu, Nghia Duy; Ngo, Tu Huy; Hoang, Phuong Vu Mai; Phan, Lan Trong; Nguyen, Thuong Vu; Nguyen, Long Thanh; Nguyen, Thinh Viet; Vien, Mai Quang; Le, Huy Xuan; Dao, Anh The; Nguyen, Trieu Bao; Pham, Duoc Tho; Nguyen, Van Thi Tuyet; Pham, Thanh Ngoc; Phan, Binh Hai; Whitaker, Brett; Do, Thuy Thi Thu; Dao, Phuong Anh; Balajee, S. Arunmozhi; Mounts, Anthony W.

In Vietnam, at the national level, the Ministry of Health General Until 2016, all SARI surveillance samples in Vietnam were tested for influenza A and influenza B, and positive samples underwent additional subtyping. Through this study, this algorithm was modified with the following change: all specimens that tested negative for influenza were tested for each of 7 non-influenza viral pathogensrespiratory syncytial virus (RSV); human metapneumovirus (hMPV); human parainfluenza viruses 1 (PIV1), 2 (PIV2), and 3 (PIV3); human rhinovirus (RV); and human adenovirus (AdV)-in a series of 7 singleplex reactions ( Figure 2 ). Following this modification, the SARI surveillance platform was referred to as expanded SARI surveillance to reflect the additional pathogens that were included in routine testing.