Author: Borkosky, Silvia S.; Whitley, Corinna; Kopp-Schneider, Annette; zur Hausen, Harald; deVilliers, Ethel-Michele
Title: Epstein-Barr Virus Stimulates Torque Teno Virus Replication: A Possible Relationship to Multiple Sclerosis Document date: 2012_2_22
ID: 0fl0heq1_5
Snippet: Influences of host-dependent factors, genotype predilection or environmental triggers on the long-term replication of TT viruses have not been investigated. Short term replication and transcription were described in cell lines of diverse origins [64] [65] [66] . We recently reported long-term replication of TT viruses with the concomitant formation and independent replication of subviral mTTV (consisting of 10-20% of the mother genome) [67] . We .....
Document: Influences of host-dependent factors, genotype predilection or environmental triggers on the long-term replication of TT viruses have not been investigated. Short term replication and transcription were described in cell lines of diverse origins [64] [65] [66] . We recently reported long-term replication of TT viruses with the concomitant formation and independent replication of subviral mTTV (consisting of 10-20% of the mother genome) [67] . We evidenced intracellular viral-like particle formation 7 days after transfection of the TTV-tth8 full-length genome into an Hodgkin's lymphoma cell line L428 [65] .
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