Author: De Jong, Cornelis N.; Saes, Lotte; Klerk, Clara P. W.; Van der Klift, Marjolein; Cornelissen, Jan J.; Broers, Annoek E. C.
Title: Etanercept for steroid-refractory acute graft-versus-host disease: A single center experience Document date: 2017_10_26
ID: 1hcp36cw_20
Snippet: Initiation of second-line treatment with etanercept. Second-line treatment with etanercept was initiated at a median of 13 days (range 5-36 days) after start of first-line treatment with high-dose steroids. Grades and organ involvement of aGvHD target organs at start of etanercept are shown in Table 2 . High-dose prednisolone was maintained until achievement of objective GvHD response, with the exception of four cases in which severe infectious c.....
Document: Initiation of second-line treatment with etanercept. Second-line treatment with etanercept was initiated at a median of 13 days (range 5-36 days) after start of first-line treatment with high-dose steroids. Grades and organ involvement of aGvHD target organs at start of etanercept are shown in Table 2 . High-dose prednisolone was maintained until achievement of objective GvHD response, with the exception of four cases in which severe infectious complications prompted earlier tapering. The median number of etanercept doses was 16 (range Table 3 .
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