Selected article for: "etanercept second line treatment and second line"
Author: De Jong, Cornelis N.; Saes, Lotte; Klerk, Clara P. W.; Van der Klift, Marjolein; Cornelissen, Jan J.; Broers, Annoek E. C.
Title: Etanercept for steroid-refractory acute graft-versus-host disease: A single center experience
  • Document date: 2017_10_26
    • ID: 1hcp36cw_34
    Snippet: In conclusion, although second-line treatment of SR-aGVHD of the gut with etanercept was associated with a promising initial response rate, overall survival appeared very poor, mainly due to progression of GVHD and opportunistic infections. Alternative strategies to prevent and treat SR-aGVHD are urgently needed and prospective studies should be prioritized to improve the grim prognosis of SR-aGVHD......
    Document: In conclusion, although second-line treatment of SR-aGVHD of the gut with etanercept was associated with a promising initial response rate, overall survival appeared very poor, mainly due to progression of GVHD and opportunistic infections. Alternative strategies to prevent and treat SR-aGVHD are urgently needed and prospective studies should be prioritized to improve the grim prognosis of SR-aGVHD.

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