Selected article for: "envelope protein and RNA virus"
Author: Liu, Xinsheng; Zhao, Donghong; Zhou, Peng; Zhang, Yongguang; Wang, Yonglu
Title: Evaluation of the Efficacy of a Recombinant Adenovirus Expressing the Spike Protein of Porcine Epidemic Diarrhea Virus in Pigs
  • Document date: 2019_10_8
    • ID: 1lxd2457_1
    Snippet: Porcine epidemic diarrhea virus (PEDV), a member of the order Nidovirales, family Coronaviridae, and genus Alphacoronavirus, is the causative agent of porcine epidemic diarrhea (PED), which is characterized by watery diarrhea, vomiting, dehydration, growth retardation, and high morbidity and mortality in suckling piglets [1, 2] . PEDV is an enveloped, single-stranded, positive-sense RNA virus, and its genome is approximately 28 kb in length and i.....
    Document: Porcine epidemic diarrhea virus (PEDV), a member of the order Nidovirales, family Coronaviridae, and genus Alphacoronavirus, is the causative agent of porcine epidemic diarrhea (PED), which is characterized by watery diarrhea, vomiting, dehydration, growth retardation, and high morbidity and mortality in suckling piglets [1, 2] . PEDV is an enveloped, single-stranded, positive-sense RNA virus, and its genome is approximately 28 kb in length and is composed of seven open reading frames (ORF1a, ORF1b, and ORF2-6) [3, 4] . Four structural proteins, namely, the spike (S) glycoprotein, membrane (M) protein, envelope (E) protein, and nucleocapsid (N) protein, and one accessory protein, ORF3, are encoded by ORF2-6 [4, 5] . Among the structural proteins, the S protein is the major envelope glycoprotein responsible for receptor binding and cell membrane fusion and entry [6, 7] . erefore, the S protein is considered the main target for neutralizing antibodies against PEDV and has been frequently used in phylogenetic analysis, establishment of serologic diagnostic methods, and development of new vaccines.

    Search related documents:
    Co phrase search for related documents
    • accessory protein and cell membrane: 1, 2, 3, 4, 5
    • accessory protein and cell membrane fusion: 1
    • accessory protein and diagnostic method: 1
    • accessory protein and diarrhea virus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
    • accessory protein and epidemic diarrhea: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
    • accessory protein and main target: 1
    • accessory protein and new vaccine: 1
    • accessory protein and open reading: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29
    • accessory protein and open reading frame: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20
    • accessory protein and PED porcine epidemic diarrhea: 1
    • accessory protein and PED porcine epidemic diarrhea causative agent: 1
    • accessory protein and PEDV diarrhea virus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
    • accessory protein and phylogenetic analysis: 1, 2, 3, 4
    • accessory protein and Porcine epidemic: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
    • accessory protein and porcine epidemic diarrhea: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
    • accessory protein and Porcine epidemic PEDV diarrhea virus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
    • accessory protein and positive sense: 1, 2, 3
    • accessory protein and positive sense RNA virus: 1
    • accessory protein and RNA virus: 1, 2, 3, 4, 5, 6, 7