Author: Frenzel, André; Hust, Michael; Schirrmann, Thomas
Title: Expression of Recombinant Antibodies Document date: 2013_7_29
ID: 06o7pa3d_32
Snippet: Overexpression of the ER resident chaperone binding protein (BiP) significantly enhanced levels of soluble and secreted IgGs in T. ni cells (143). Enhanced secretion of IgGs was also achieved by coexpression of protein disulfide isomerase (PDI) or the human cytosolic chaperone hsp70 in T. ni cells (138)......
Document: Overexpression of the ER resident chaperone binding protein (BiP) significantly enhanced levels of soluble and secreted IgGs in T. ni cells (143). Enhanced secretion of IgGs was also achieved by coexpression of protein disulfide isomerase (PDI) or the human cytosolic chaperone hsp70 in T. ni cells (138).
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