Selected article for: "antibody expression and expression system"
Author: Frenzel, André; Hust, Michael; Schirrmann, Thomas
Title: Expression of Recombinant Antibodies
  • Document date: 2013_7_29
    • ID: 06o7pa3d_51
    Snippet: Transient expression of an antibody in plants can be achieved using viral vectors. The main problem with this approach is the low infectivity with these vectors. Therefore, the more efficient transfer of A. tumefaciens was combined with the speed and high expression rate of plant RNA viruses (207) . This system has been used for the expression of monoclonal antibodies in Nicotiana benthamiana with yields up to 0.5 g/kg fresh weight (208) ......
    Document: Transient expression of an antibody in plants can be achieved using viral vectors. The main problem with this approach is the low infectivity with these vectors. Therefore, the more efficient transfer of A. tumefaciens was combined with the speed and high expression rate of plant RNA viruses (207) . This system has been used for the expression of monoclonal antibodies in Nicotiana benthamiana with yields up to 0.5 g/kg fresh weight (208) .

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