Author: Camacho, Anton; Ballesteros, Sébastien; Graham, Andrea L.; Carrat, Fabrice; Ratmann, Oliver; Cazelles, Bernard
Title: Explaining rapid reinfections in multiple-wave influenza outbreaks: Tristan da Cunha 1971 epidemic as a case study Document date: 2011_12_22
ID: 12y420k8_6
Snippet: Our study reveals that, when demographic stochasticity is appropriately accounted for, the second epidemic wave can only be explained with mechanisms attributable to delayed or deficient humoral immune responses. Our strictly mechanistic interpretations enable us to quantitatively compare our results with empirical data and we close with an evaluation of the potential genetic and ecological determinants of variation in host susceptibility......
Document: Our study reveals that, when demographic stochasticity is appropriately accounted for, the second epidemic wave can only be explained with mechanisms attributable to delayed or deficient humoral immune responses. Our strictly mechanistic interpretations enable us to quantitatively compare our results with empirical data and we close with an evaluation of the potential genetic and ecological determinants of variation in host susceptibility.
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