Author: Huang, Nan-Chieh; Hung, Wan-Ting; Tsai, Wei-Lun; Lai, Feng-Yi; Lin, You-Sheng; Huang, Mei-Shu; Chen, Jih-Jung; Lin, Wei-Yu; Weng, Jing-Ru; Chang, Tsung-Hsien
Title: Ficus septica plant extracts for treating Dengue virus in vitro Document date: 2017_6_8
ID: 1a3cmi9i_21
Snippet: ( Fig. 2A) . FS-(L)-M significantly inhibited DENV-1 (IC 50 = 17.4 ± 4.6 µg/ml) and DENV-2 (IC 50 = 15.8 ± 2.5 µg/ml) but not AiV (Fig. 2B) . Thus, FS-(L)-M directly impaired enveloped viral particles but not non-enveloped virus. In this study, F. septica extracts had a promising anti-DENV-1 and -DENV-2 effect. Nevertheless, the non-enveloped picornavirus AiV was not efficiently inhibited by F. septica extract. Thus, F. septica would be a pos.....
Document: ( Fig. 2A) . FS-(L)-M significantly inhibited DENV-1 (IC 50 = 17.4 ± 4.6 µg/ml) and DENV-2 (IC 50 = 15.8 ± 2.5 µg/ml) but not AiV (Fig. 2B) . Thus, FS-(L)-M directly impaired enveloped viral particles but not non-enveloped virus. In this study, F. septica extracts had a promising anti-DENV-1 and -DENV-2 effect. Nevertheless, the non-enveloped picornavirus AiV was not efficiently inhibited by F. septica extract. Thus, F. septica would be a possible antiviral drug candidate against enveloped virus, such as DENV.
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