Selected article for: "gene expression and reporter gene expression"
Author: Brauburger, Kristina; Hume, Adam J.; Mühlberger, Elke; Olejnik, Judith
Title: Forty-Five Years of Marburg Virus Research
  • Document date: 2012_10_1
    • ID: 0hlj6r10_40
    Snippet: The matrix protein VP40 is encoded by the third MARV gene and is the counterpart of the M proteins of other NNS RNA viruses. VP40 plays a major role in the formation of virions by redistributing nucleocapsids from the perinuclear region to the plasma membrane, recruiting GP to the sites of budding, and mediating particle release [110] [111] [112] . Overexpression of VP40 led to reduced reporter gene expression of MARV minigenomes, suggesting a re.....
    Document: The matrix protein VP40 is encoded by the third MARV gene and is the counterpart of the M proteins of other NNS RNA viruses. VP40 plays a major role in the formation of virions by redistributing nucleocapsids from the perinuclear region to the plasma membrane, recruiting GP to the sites of budding, and mediating particle release [110] [111] [112] . Overexpression of VP40 led to reduced reporter gene expression of MARV minigenomes, suggesting a regulatory role of VP40 in transcription and/or replication [113] .

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