Author: Mazumder, Tarikul Huda; Chakraborty, Supriyo
Title: Gaining Insights into the Codon Usage Patterns of TP53 Gene across Eight Mammalian Species Document date: 2015_3_25
ID: 1qtqergw_2
Snippet: The nucleus of a cell is the main store house of tumor protein p53 where it binds to DNA. When any damage occurs in the DNA of a cell by some external agents like toxic chemicals, radiation, exposure to sun light or ultra violet rays, p53 plays the crucial role in activating other genes and inhibits cell cycle to repair the damage [4] . In case of failure of DNA repair, the tumor protein p53 prevents the cell from dividing and provokes signals to.....
Document: The nucleus of a cell is the main store house of tumor protein p53 where it binds to DNA. When any damage occurs in the DNA of a cell by some external agents like toxic chemicals, radiation, exposure to sun light or ultra violet rays, p53 plays the crucial role in activating other genes and inhibits cell cycle to repair the damage [4] . In case of failure of DNA repair, the tumor protein p53 prevents the cell from dividing and provokes signals to a wide variety of genes that contribute to TP53 mediated cell death i.e., apoptosis [5] .
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