Selected article for: "astrocytes IFN response and IFN response"
Author: Lindqvist, Richard; Mundt, Filip; Gilthorpe, Jonathan D.; Wölfel, Silke; Gekara, Nelson O.; Kröger, Andrea; Överby, Anna K.
Title: Fast type I interferon response protects astrocytes from flavivirus infection and virus-induced cytopathic effects
  • Document date: 2016_10_24
    • ID: 09tcnsxv_59
    Snippet: Our results show that astrocytes mount a rapid type I IFN response upon flavivirus infection that inhibits viral spread and replication. The IFN response also protects astrocytes from virus-induced cell death. We further propose that astrocytes are important IFN producers in flavivirus infection, which can sense the viral infection and then mediate a local IFN response within the CNS, which could protect not only astrocytes but also other CNS res.....
    Document: Our results show that astrocytes mount a rapid type I IFN response upon flavivirus infection that inhibits viral spread and replication. The IFN response also protects astrocytes from virus-induced cell death. We further propose that astrocytes are important IFN producers in flavivirus infection, which can sense the viral infection and then mediate a local IFN response within the CNS, which could protect not only astrocytes but also other CNS resident cells.

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