Selected article for: "cell process and mammalian cell"

Author: Frenzel, André; Hust, Michael; Schirrmann, Thomas
Title: Expression of Recombinant Antibodies
  • Document date: 2013_7_29
  • ID: 06o7pa3d_48
    Snippet: The development of transgenic plants for the expression of recombinant antibodies is becoming interesting, especially when high amounts are required. Up-scaling of this production system can be achieved more easily compared to other systems such as mammalian cell culture, where up-scaling of the fermentation process leads to increasing production costs. In theory, the costs of an IgA expressed in plants are only 1-10% compared to the expression i.....
    Document: The development of transgenic plants for the expression of recombinant antibodies is becoming interesting, especially when high amounts are required. Up-scaling of this production system can be achieved more easily compared to other systems such as mammalian cell culture, where up-scaling of the fermentation process leads to increasing production costs. In theory, the costs of an IgA expressed in plants are only 1-10% compared to the expression in hybridoma cells (185) .

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