Selected article for: "define time point and time point"
Author: Lindqvist, Richard; Mundt, Filip; Gilthorpe, Jonathan D.; Wölfel, Silke; Gekara, Nelson O.; Kröger, Andrea; Överby, Anna K.
Title: Fast type I interferon response protects astrocytes from flavivirus infection and virus-induced cytopathic effects
  • Document date: 2016_10_24
    • ID: 09tcnsxv_36
    Snippet: In order to define the time point after infection at which astrocytes initiate an antiviral response and limit viral spread in astrocytes, a TBEV-based bioassay on astrocytes was developed. Pretreated astrocytes were infected, and the numbers of infected cells were quantified at 48 hpi (Fig. 3f ) . The supernatants showed an inhibitory effect as early as 6 hpi on WT, but not on IFNAR −/− cells, suggesting a very early type I IFNmediated antiv.....
    Document: In order to define the time point after infection at which astrocytes initiate an antiviral response and limit viral spread in astrocytes, a TBEV-based bioassay on astrocytes was developed. Pretreated astrocytes were infected, and the numbers of infected cells were quantified at 48 hpi (Fig. 3f ) . The supernatants showed an inhibitory effect as early as 6 hpi on WT, but not on IFNAR −/− cells, suggesting a very early type I IFNmediated antiviral effect.

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