Author: Fisher, Colleen A.; Bhattarai, Eric K.; Osterstock, Jason B.; Dowd, Scot E.; Seabury, Paul M.; Vikram, Meenu; Whitlock, Robert H.; Schukken, Ynte H.; Schnabel, Robert D.; Taylor, Jeremy F.; Womack, James E.; Seabury, Christopher M.
Title: Evolution of the Bovine TLR Gene Family and Member Associations with Mycobacterium avium Subspecies paratuberculosis Infection Document date: 2011_11_30
ID: 0lut2w17_27
Snippet: Our detailed analysis of the haplotype structure, LD architecture, and tagSNP/Indel prediction for all 10 bovine TLR genes will enable studies aimed at assessing the statistical and functional relationships between validated variation, and differential susceptibility to infectious disease [19] [20] [21] [22] [23] [24] [25] [26] [27] 46] (Table 5) . Moreover, because extensive haplotype sharing was confidently predicted for specialized beef and da.....
Document: Our detailed analysis of the haplotype structure, LD architecture, and tagSNP/Indel prediction for all 10 bovine TLR genes will enable studies aimed at assessing the statistical and functional relationships between validated variation, and differential susceptibility to infectious disease [19] [20] [21] [22] [23] [24] [25] [26] [27] 46] (Table 5) . Moreover, because extensive haplotype sharing was confidently predicted for specialized beef and dairy cattle breeds, the deliverables of this study will broadly impact many facets of bovine health research, including the potential for marker-assisted vaccination; using genotypes as indicator variables for enhanced vaccine design or as predictors of animal response.
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