Selected article for: "protein expression and recombinant protein"
Author: Brauburger, Kristina; Hume, Adam J.; Mühlberger, Elke; Olejnik, Judith
Title: Forty-Five Years of Marburg Virus Research
  • Document date: 2012_10_1
    • ID: 0hlj6r10_108
    Snippet: A third of EBOV-infected NHPs survived, however, following treatment with recombinant nematode coagulant protein 2, while only one of six MARV-infected animals survived [12, 263] . Treatment using antisense technology to block viral protein expression using phosphorodiamidate morpholino oligomers (PMO) beginning 30 to 60 minutes after MARV infection completely protected NHPs [264] . Additionally, a small molecule inhibitor showed complete protect.....
    Document: A third of EBOV-infected NHPs survived, however, following treatment with recombinant nematode coagulant protein 2, while only one of six MARV-infected animals survived [12, 263] . Treatment using antisense technology to block viral protein expression using phosphorodiamidate morpholino oligomers (PMO) beginning 30 to 60 minutes after MARV infection completely protected NHPs [264] . Additionally, a small molecule inhibitor showed complete protection of MARV-infected mice when administered 24h after infection but has not been tested in NHPs [265] .

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