Author: Vidaña, Beatriz; Martínez, Jorge; Martínez-Orellana, Pamela; García Migura, Lourdes; Montoya, María; Martorell, Jaime; Majó, Natàlia
Title: Heterogeneous pathological outcomes after experimental pH1N1 influenza infection in ferrets correlate with viral replication and host immune responses in the lung Document date: 2014_8_28
ID: 0hyg403m_48
Snippet: To determine which cells were involved in the increases in pro-apoptotic gene expression in the animals with severe lung lesions, IHC using the anti-caspase 3 antibody was performed. As expected, the numbers of apoptotic cells were elevated in the ferrets with severe lung lesions compared to the animals with mild lesions, but the positive cells were mainly consistent with macrophages and neutrophils ( Figure 6B and C), which accords with the phag.....
Document: To determine which cells were involved in the increases in pro-apoptotic gene expression in the animals with severe lung lesions, IHC using the anti-caspase 3 antibody was performed. As expected, the numbers of apoptotic cells were elevated in the ferrets with severe lung lesions compared to the animals with mild lesions, but the positive cells were mainly consistent with macrophages and neutrophils ( Figure 6B and C), which accords with the phagocytic cell averages observed in each pathological group.
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