Selected article for: "cytokine gene and gene expression"

Author: Vidaña, Beatriz; Martínez, Jorge; Martínez-Orellana, Pamela; García Migura, Lourdes; Montoya, María; Martorell, Jaime; Majó, Natàlia
Title: Heterogeneous pathological outcomes after experimental pH1N1 influenza infection in ferrets correlate with viral replication and host immune responses in the lung
  • Document date: 2014_8_28
  • ID: 0hyg403m_57
    Snippet: Several studies have identified common cytokine gene expression profiles that are involved in neutrophil recruitment, stimulation of T cell proliferation and CD8+ cell-mediated inflammation in influenza-associated pathology [17, 52, 53] . Gene expression profiles that promote T helper (Th) 1 cell responses have also been shown to be closely related to poor outcomes in severe cases of pH1N1 infection [17, 54, 55] . Here, the animals that developed.....
    Document: Several studies have identified common cytokine gene expression profiles that are involved in neutrophil recruitment, stimulation of T cell proliferation and CD8+ cell-mediated inflammation in influenza-associated pathology [17, 52, 53] . Gene expression profiles that promote T helper (Th) 1 cell responses have also been shown to be closely related to poor outcomes in severe cases of pH1N1 infection [17, 54, 55] . Here, the animals that developed severe lung lesions also presented with elevated expressions of Th1 response-inducers (CCL5, CCL3, CXCL10 and IFNγ), while no differences in the expression of the Th2 response-inducer CCL2 were observed between animals with severe and mild lesions.

    Search related documents:
    Co phrase search for related documents