High Prevalence of Viral Infections Among Hospitalized Pneumonia Patients in Equatorial Sarawak, Malaysia

Toh, Teck-Hock; Hii, King-Ching; Fieldhouse, Jane K; Ting, Jakie; Berita, Antoinette; Nguyen, Tham Thi; Wong, See-Chang; Wong, Toh-Mee; Lim, Wei-Honn; Ha, Siaw-Jing; Lau, Chuet-Zou; Kong, Sing-Ling; Bailey, Emily S; Warkentien, Tyler E; Husain, Tupur S; Gray, Gregory C

The month of enrollment was a statistically significant risk factor for most virus outcomes, including RSV-A, RSV-B, IAV, and AdV (Tables 4 and 5 and Supplementary Tables 3 and 4 ). Respiratory syncytial virus subtype A was most prevalent during the first month of enrollment, June-July 2017 with an adjusted OR of 7.2 (95% CI, 1.6-33.5) compared with RSV-A detection by rRT-PCR in November-December 2017 (Table 4 ). In contrast, there was a very low detection of RSV-B in June-July 2017 (see Supplementary Figure 2 ). Compared to June-July 2017, RSV-B had an increased adjusted OR beginning mid-February, with an adjusted OR of 23.1 (95% CI, 2.9-185.6) between April 15 and May 14, 2018 (Table 5) . We detected AdV in over 30% of the 72 specimens collected from April 15 to May 14, 2018. Compared to the month of October-November 2017, there was an increased adjusted OR of 16.9 (95% CI, 2.1-133.4) of AdV infection during the month of April-May.