Author: Woolhouse, Mark; Scott, Fiona; Hudson, Zoe; Howey, Richard; Chase-Topping, Margo
Title: Human viruses: discovery and emergence Document date: 2012_10_19
ID: 0i59vlyd_37
Snippet: To test this idea, we first carried out a comprehensive review of the peer reviewed literature and identified 88 human virus species for which at least one cell receptor has been identified. Although this is only 40 per cent of the species of interest, 21 (of 23) families were represented; so this set contains a good cross-section of relevant taxonomic diversity. Of these 88 species, 22 use non-protein receptors (e.g. heparin sulphate) and, of th.....
Document: To test this idea, we first carried out a comprehensive review of the peer reviewed literature and identified 88 human virus species for which at least one cell receptor has been identified. Although this is only 40 per cent of the species of interest, 21 (of 23) families were represented; so this set contains a good cross-section of relevant taxonomic diversity. Of these 88 species, 22 use non-protein receptors (e.g. heparin sulphate) and, of the remainder, two of the proteins were not entered in the UniProt database [40] (making it impossible to determine whether the protein was 'conserved' or not-see below for details), leaving 64 species from 16 families.
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