Author: Yichun Wang; Usha Kadiyala; Zhibei Qu; Paolo Elvati; Christopher Altheim; Nicholas A. Kotov; Angela Violi; J. Scott VanEpps
Title: Anti-biofilm Activity of Graphene Quantum Dots via Self-Assembly with Bacterial Amyloid Proteins Document date: 2019_2_19
ID: e0sxynb1_6
Snippet: GQDs used in this study had a diameter of 2-8 nm 15 and carried nine carboxyl edge-groups on average. (Figure S1 ) To investigate how GQDs affect amyloid-rich biofilms, S. aureus biofilms were grown in peptone-NaCl-glucose (PNG) media for four days in flow cells. 32 S. aureus biofilms were also grown in tryptic soy broth supplemented with glucose (TSBG) media that inhibits amyloid synthesis as a negative control. Confocal images showed that S. au.....
Document: GQDs used in this study had a diameter of 2-8 nm 15 and carried nine carboxyl edge-groups on average. (Figure S1 ) To investigate how GQDs affect amyloid-rich biofilms, S. aureus biofilms were grown in peptone-NaCl-glucose (PNG) media for four days in flow cells. 32 S. aureus biofilms were also grown in tryptic soy broth supplemented with glucose (TSBG) media that inhibits amyloid synthesis as a negative control. Confocal images showed that S. aureus formed biofilm covering the entire surface of the flow cell in both TSBG and PNG without GQDs (Figure 1a, d) .
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