Selected article for: "copd exacerbation and secondary bacterial infection"
Author: Aran Singanayagam; Su-Ling Loo; Maria Calderazzo; Lydia J Finney; Maria-Belen Trujillo Torralbo; Eteri Bakhsoliani; Jason Girkin; Punnam Veerati; Prabuddha S Pathinayake; Kristy S Nichol; Andrew Reid; Joseph Foottit; Sebastian L Johnston; Nathan W Bartlett; Patrick Mallia
Title: Anti-microbial immunity is impaired in COPD patients with frequent exacerbations
  • Document date: 2019_5_9
    • ID: 72jzqm86_32
    Snippet: There were no differences in sputum 16S bacterial loads between frequent and infrequent exacerbators at baseline or exacerbation onset (Fig 4a&b) . However, frequent exacerbators had a significant increase (~1 log) in bacterial loads at 2 weeks post exacerbation onset (Fig 4c) , suggesting that this COPD subgroup may have increased likelihood of secondary bacterial infection during virusinduced exacerbation......
    Document: There were no differences in sputum 16S bacterial loads between frequent and infrequent exacerbators at baseline or exacerbation onset (Fig 4a&b) . However, frequent exacerbators had a significant increase (~1 log) in bacterial loads at 2 weeks post exacerbation onset (Fig 4c) , suggesting that this COPD subgroup may have increased likelihood of secondary bacterial infection during virusinduced exacerbation.

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