Selected article for: "linear regression and Multivariate linear regression"
Author: Pizzutto, Susan J.; Upham, John W.; Yerkovich, Stephanie T.; Chang, Anne B.
Title: High Pulmonary Levels of IL-6 and IL-1ß in Children with Chronic Suppurative Lung Disease Are Associated with Low Systemic IFN-? Production in Response to Non-Typeable Haemophilus influenzae
  • Document date: 2015_6_12
    • ID: 19jo817j_26
    Snippet: Using a cut off of p<0.1 from the univariate analyses described in Tables 2 and 3 above and considering confounding factors, we combined the inflammatory markers in the BAL and blood into a multivariate linear regression model. We found that in vitro IFN-γ production by blood mononuclear cells in response to NTHi was significantly and inversely associated with BAL IL-1β (β = -0.023; 95%CI -0.04, -0.01; p = 0.001) and IL-6 (β = -0.316; 95%CI -.....
    Document: Using a cut off of p<0.1 from the univariate analyses described in Tables 2 and 3 above and considering confounding factors, we combined the inflammatory markers in the BAL and blood into a multivariate linear regression model. We found that in vitro IFN-γ production by blood mononuclear cells in response to NTHi was significantly and inversely associated with BAL IL-1β (β = -0.023; 95%CI -0.04, -0.01; p = 0.001) and IL-6 (β = -0.316; 95%CI -0.49, -0.14; p = 0.001). In contrast, BAL IL-8, IP-10, neutrophil % and infection status, as well as blood platelets were no longer independent predictors of the IFN-γ response to NTHi by blood mononuclear cells

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