Selected article for: "antibacterial activity and MIC value"
Author: Marcotullio, Maria Carla; Pelosi, Azzurra; Curini, Massimo
Title: Hinokinin, an Emerging Bioactive Lignan
  • Document date: 2014_9_17
    • ID: 04kh4yzy_27
    Snippet: Hinokinin (1) has been studied for its bioactivity against several other microorganisms. For example, Silva et al. examined the activity of this compound against oral pathogens such as Enterococcus faecalis, Candida albicans and several Streptococcus strains (see Table 5 ). It can be pointed out from data reported in Table 5 that, although chlorhexidine is much more active than hinokinin, 1 nevertheless showed a discrete antimicrobial activity [9.....
    Document: Hinokinin (1) has been studied for its bioactivity against several other microorganisms. For example, Silva et al. examined the activity of this compound against oral pathogens such as Enterococcus faecalis, Candida albicans and several Streptococcus strains (see Table 5 ). It can be pointed out from data reported in Table 5 that, although chlorhexidine is much more active than hinokinin, 1 nevertheless showed a discrete antimicrobial activity [95] . Considering this antibacterial activity of hinokinin, Silva et al. evaluated the anti-mycobacterial activity of 1 and others lignans [96] . Hinokinin showed to be moderately active against M. tuberculosis, with a MIC value equal to 62.5 μg/mL and inactive against M. kansasii and M. avium (MIC 2000 μg/mL and 500 μg/mL, respectively).

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