Author: Bekpen, Cemalettin; Tautz, Diethard
Title: Human core duplicon gene families: game changers or game players? Document date: 2019_9_16
ID: 0fjh10v7_62
Snippet: The LRRC37 (leucine-rich repeat containing 37A) gene family has expanded on human chromosome 17 [4] from a single ancestral copy in other mammals [69, 70] . In humans, this family's gene structure is highly fragmented, and only 8 of 18 copies are complete. Two of these eight complete LRRC37 genes can be classified as the LRRC37B type. The number of the duplication segments is variable within the primate lineage; there are 4, 7, 10 and 18 copies i.....
Document: The LRRC37 (leucine-rich repeat containing 37A) gene family has expanded on human chromosome 17 [4] from a single ancestral copy in other mammals [69, 70] . In humans, this family's gene structure is highly fragmented, and only 8 of 18 copies are complete. Two of these eight complete LRRC37 genes can be classified as the LRRC37B type. The number of the duplication segments is variable within the primate lineage; there are 4, 7, 10 and 18 copies in marmoset, macaque, orangutan and human, respectively [70] . Similar to the SPATA31 genes, the N-terminal region (especially exon 1) of LRRC37A has acquired novel structures and promoters in the primate lineage [69] .
Search related documents:
Co phrase search for related documents- ancestral copy and human chromosome: 1
- family gene structure and gene family: 1
- family gene structure and gene structure: 1
- gene family and human chromosome: 1, 2, 3, 4, 5, 6, 7
- gene family and leucine rich repeat: 1
- gene family and novel structure: 1
- gene structure and novel structure: 1, 2, 3
- human chromosome and primate lineage: 1
Co phrase search for related documents, hyperlinks ordered by date