Author: Pizzutto, Susan J.; Upham, John W.; Yerkovich, Stephanie T.; Chang, Anne B.
Title: High Pulmonary Levels of IL-6 and IL-1ß in Children with Chronic Suppurative Lung Disease Are Associated with Low Systemic IFN-? Production in Response to Non-Typeable Haemophilus influenzae Document date: 2015_6_12
ID: 19jo817j_24
Snippet: On univariate analysis for the BAL data ( Table 2 and Fig 1) , % neutrophils, IL-1β, IL-6, IL-8, IP-10, NTHi infection and respiratory viruses were inversely associated with NTHi-specific IFN-γ production by blood mononuclear cells. On univariate analysis for the systemic inflammation data (Table 3) , blood platelet levels (although within the normal clinical reference range) were inversely associated with NTHispecific IFN-γ production by bloo.....
Document: On univariate analysis for the BAL data ( Table 2 and Fig 1) , % neutrophils, IL-1β, IL-6, IL-8, IP-10, NTHi infection and respiratory viruses were inversely associated with NTHi-specific IFN-γ production by blood mononuclear cells. On univariate analysis for the systemic inflammation data (Table 3) , blood platelet levels (although within the normal clinical reference range) were inversely associated with NTHispecific IFN-γ production by blood mononuclear cells. In contrast, blood leukocyte numbers, CRP and serum inflammatory mediators were not associated with NTHi-specific IFNγ production.
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