Author: Smith, Steven B.; Dampier, William; Tozeren, Aydin; Brown, James R.; Magid-Slav, Michal
Title: Identification of Common Biological Pathways and Drug Targets Across Multiple Respiratory Viruses Based on Human Host Gene Expression Analysis Document date: 2012_3_14
ID: 100ir651_57
Snippet: We performed complete linkage and correlation distance hierarchical clustering using ArrayStudio on quantile normalized fold change values to determine the separation qualities of the analyzed data [100] . Clustering was performed on genes that had expression values for at least 90% of the total number of comparisons. We used the Matlab function 'knnimpute' to impute missing fold change values using k-Nearest Neighbors estimation (MATLAB version .....
Document: We performed complete linkage and correlation distance hierarchical clustering using ArrayStudio on quantile normalized fold change values to determine the separation qualities of the analyzed data [100] . Clustering was performed on genes that had expression values for at least 90% of the total number of comparisons. We used the Matlab function 'knnimpute' to impute missing fold change values using k-Nearest Neighbors estimation (MATLAB version 7.11 (R2010b), Mathworks, Cambridge MA, 2010) [101, 102] .
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