Author: Marcotullio, Maria Carla; Pelosi, Azzurra; Curini, Massimo
Title: Hinokinin, an Emerging Bioactive Lignan Document date: 2014_9_17
ID: 04kh4yzy_32
Snippet: Resende also showed that hinokinin has a protective effect in preventing clastogenic damage caused by methyl methanesulfonate (MMS), with the percent reduction ranging from 37.4% to 57.6% [100] . Mutagenic activity was evaluated by the Ames test, using the Salmonella typhimurium tester strains TA98, TA100, TA97a and TA102, using five different concentrations of hinokinin (9.75-78.0 μg/plate) selected on the basis of a preliminary toxicity test. .....
Document: Resende also showed that hinokinin has a protective effect in preventing clastogenic damage caused by methyl methanesulfonate (MMS), with the percent reduction ranging from 37.4% to 57.6% [100] . Mutagenic activity was evaluated by the Ames test, using the Salmonella typhimurium tester strains TA98, TA100, TA97a and TA102, using five different concentrations of hinokinin (9.75-78.0 μg/plate) selected on the basis of a preliminary toxicity test. The mutagenicity assays show that 1 did not induce any increase in the number of revertant colonies relative to the negative control, indicating the absence of any mutagenic activity.
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