Author: Pattyn, Els; Verhee, Annick; Uyttendaele, Isabel; Piessevaux, Julie; Timmerman, Evy; Gevaert, Kris; Vandekerckhove, Joël; Peelman, Frank; Tavernier, Jan
Title: HyperISGylation of Old World Monkey ISG15 in Human Cells Document date: 2008_6_18
ID: 1eksm537_21
Snippet: The isg15 gene emerged upon the duplication of an Ub dimer and insertion in an IFN-controlled area [39] . In sharp contrast with Ub itself, of which 72 of the 76 amino acid are invariant between animals, plants and fungi [40] , ISG15 is not well conserved between species [2] ......
Document: The isg15 gene emerged upon the duplication of an Ub dimer and insertion in an IFN-controlled area [39] . In sharp contrast with Ub itself, of which 72 of the 76 amino acid are invariant between animals, plants and fungi [40] , ISG15 is not well conserved between species [2] .
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