Selected article for: "differential expression and quality control"

Author: Smith, Steven B.; Dampier, William; Tozeren, Aydin; Brown, James R.; Magid-Slav, Michal
Title: Identification of Common Biological Pathways and Drug Targets Across Multiple Respiratory Viruses Based on Human Host Gene Expression Analysis
  • Document date: 2012_3_14
  • ID: 100ir651_11
    Snippet: No single dataset exhibited overall poor Quality Control (QC), and therefore, all 19 datasets representing 42 comparison groups were analyzed for differential expression. However, QC analysis across all candidate datasets revealed two outliers in GSE17156 (samples GSM429252 and GSM429279), two in GSE11348 (samples GSM286647 and GSM286733), and one outlier each in dataset GSE24132 [26] (sample GSM594166), GSE1739 (sample GSM30367), and GSE19580 (s.....
    Document: No single dataset exhibited overall poor Quality Control (QC), and therefore, all 19 datasets representing 42 comparison groups were analyzed for differential expression. However, QC analysis across all candidate datasets revealed two outliers in GSE17156 (samples GSM429252 and GSM429279), two in GSE11348 (samples GSM286647 and GSM286733), and one outlier each in dataset GSE24132 [26] (sample GSM594166), GSE1739 (sample GSM30367), and GSE19580 (sample GSM487986) for a total of seven samples removed from five different datasets.

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