Author: Pizzutto, Susan J.; Upham, John W.; Yerkovich, Stephanie T.; Chang, Anne B.
Title: High Pulmonary Levels of IL-6 and IL-1ß in Children with Chronic Suppurative Lung Disease Are Associated with Low Systemic IFN-? Production in Response to Non-Typeable Haemophilus influenzae Document date: 2015_6_12
ID: 19jo817j_30
Snippet: The mechanism driving the relationship described is likely complex. The capacity for IFN-γ production was inversely associated with airway inflammation but the direction of this association (i.e. cause or effect) is unknown. One possible mechanism for the former involves regulating the transition between the inflammatory and adaptive response. These processes are integral for homeostasis through rapid identification and elimination of the invadi.....
Document: The mechanism driving the relationship described is likely complex. The capacity for IFN-γ production was inversely associated with airway inflammation but the direction of this association (i.e. cause or effect) is unknown. One possible mechanism for the former involves regulating the transition between the inflammatory and adaptive response. These processes are integral for homeostasis through rapid identification and elimination of the invading pathogen and prompt resolution of inflammation, measured by markers such as IL-1β and IL-6.
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