Author: Lelli, Davide; Lavazza, Antonio; Prosperi, Alice; Sozzi, Enrica; Faccin, Francesca; Baioni, Laura; Trogu, Tiziana; Cavallari, Gian Luca; Mauri, Matteo; Gibellini, Anna Maria; Chiapponi, Chiara; Moreno, Ana
Title: Hypsugopoxvirus: A Novel Poxvirus Isolated from Hypsugo savii in Italy Document date: 2019_6_19
ID: 1axsebya_25
Snippet: It is noteworthy that PTPV and EHPV were isolated from megabat hosts (Pteropus scapulatus and Eidolon helvum, respectively), whereas EPTV and HYPV were isolated from microbats (Eptesicus fuscus and Hypsugo savii, respectively). While EHPV was detected in apparently healthy bats, the other viruses were identified in sick bats and their association with the pathological condition was assumed. Specifically, clinical symptoms of EPTV in Eptesicus fus.....
Document: It is noteworthy that PTPV and EHPV were isolated from megabat hosts (Pteropus scapulatus and Eidolon helvum, respectively), whereas EPTV and HYPV were isolated from microbats (Eptesicus fuscus and Hypsugo savii, respectively). While EHPV was detected in apparently healthy bats, the other viruses were identified in sick bats and their association with the pathological condition was assumed. Specifically, clinical symptoms of EPTV in Eptesicus fuscus manifested in the form of joint swelling and increased lethargy [10] . PTPV-infected Pteropus scapulatus presented vesicular to nodular skin lesions on the wing membranes that are typical of poxvirus infections [13] . HYPV was detected in a bat showing pathological healing of the humerus fracture associated with osteomalacia and calcium deficiency. Neither symptom was directly linked to fatality and thus the capability of these viruses still needs to be ascertained, including the role of HYPV in causing deadly disease in bats.
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