Selected article for: "causative agent and diarrhea cause"
Author: Takenouchi, Takato; Kitani, Hiroshi; Suzuki, Shunichi; Nakai, Michiko; Fuchimoto, Dai-ichiro; Tsukimoto, Mitsutoshi; Shinkai, Hiroki; Sato, Mitsuru; Uenishi, Hirohide
Title: Immortalization and Characterization of Porcine Macrophages That Had Been Transduced with Lentiviral Vectors Encoding the SV40 Large T Antigen and Porcine Telomerase Reverse Transcriptase
  • Document date: 2017_8_21
    • ID: 0cqtxqjv_5
    Snippet: Since the domestic pig is an important agricultural animal, infectious diseases that affect swine, such as porcine reproductive and respiratory syndrome (PRRS), porcine epidemic diarrhea (PED), and bacterial infections, can cause severe economic losses in the global swine industry. The PRRS virus (PRRSV) is the causative agent of PRRS and targets porcine monocyte/macrophage lineage cells. CD163 is an essential receptor for this virus infection (3.....
    Document: Since the domestic pig is an important agricultural animal, infectious diseases that affect swine, such as porcine reproductive and respiratory syndrome (PRRS), porcine epidemic diarrhea (PED), and bacterial infections, can cause severe economic losses in the global swine industry. The PRRS virus (PRRSV) is the causative agent of PRRS and targets porcine monocyte/macrophage lineage cells. CD163 is an essential receptor for this virus infection (3). The PED virus, a coronavirus, is the causative agent of PED and infects macrophages and disrupts their functions (4). In addition, bacterial pathogens, such as Brucella and Salmonella, also target macrophages in swine and impair their functions, which facilitate the invasion and proliferation of such pathogens (5, 6) .

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