Selected article for: "acute respiratory syndrome and human immunodeficiency virus"
Author: Baha Abdalhamid; Christopher R Bilder; Emily L McCutchen; Steven H Hinrichs; Scott A Koepsell; Peter C Iwen
Title: Assessment of Specimen Pooling to Conserve SARS CoV-2 Testing Resources
  • Document date: 2020_4_6
    • ID: fmbowr9g_12
    Snippet: The copyright holder for this preprint (which was not peer-reviewed) is the . https: //doi.org/10.1101 //doi.org/10. /2020 Since the first detection in Wuhan, China in December 2019, severe acute respiratory 43 syndrome coronavirus 2 (SARS-CoV-2), the pathogen of coronavirus diseases 2019 , 44 has spread worldwide to now be considered a pandemic 1, 2 swabs. The second step in the assay employs reverse transcription and amplification using a real .....
    Document: The copyright holder for this preprint (which was not peer-reviewed) is the . https: //doi.org/10.1101 //doi.org/10. /2020 Since the first detection in Wuhan, China in December 2019, severe acute respiratory 43 syndrome coronavirus 2 (SARS-CoV-2), the pathogen of coronavirus diseases 2019 , 44 has spread worldwide to now be considered a pandemic 1, 2 swabs. The second step in the assay employs reverse transcription and amplification using a real 54 time PCR instrumentation. The assay therefore requires two kits, one for extraction and another 55 for amplification of the target and detection. We investigated whether a strategy used in the testing 56 of blood prior to transfusion could have application for conservation of scarce reagents for the 57 SARS CoV-2 assay 4,5 . The process of group testing that employs sample pooling is used for 58 detection of the human immunodeficiency virus, and hepatitis B and C viruses 4 in blood products.

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