Author: Baha Abdalhamid; Christopher R Bilder; Emily L McCutchen; Steven H Hinrichs; Scott A Koepsell; Peter C Iwen
Title: Assessment of Specimen Pooling to Conserve SARS CoV-2 Testing Resources Document date: 2020_4_6
ID: fmbowr9g_24
Snippet: The CDC RT-PCR assay was used in this study to detect SARS- author/funder, who has granted medRxiv a license to display the preprint in perpetuity. were positive within a range of 0 Ct to 5.03 Ct difference from the original samples (Table 1) . To 92 examine this approach in a clinical situation, 60 specimens from individuals at risk for COVID-19 93 as determined by the public health department were separated randomly into 12 pools, which were 94.....
Document: The CDC RT-PCR assay was used in this study to detect SARS- author/funder, who has granted medRxiv a license to display the preprint in perpetuity. were positive within a range of 0 Ct to 5.03 Ct difference from the original samples (Table 1) . To 92 examine this approach in a clinical situation, 60 specimens from individuals at risk for COVID-19 93 as determined by the public health department were separated randomly into 12 pools, which were 94 processed as described. Two of the pools were characterized as "2019-nCoV detected" by the The practical application of this process was confirmed with 60 samples from the 108 community resulting in the saving of reagents and personnel time that could expand testing to an 109 additional 38 samples. Assuming a consistent positivity rate, this strategy would expand testing 110 All rights reserved. No reuse allowed without permission. author/funder, who has granted medRxiv a license to display the preprint in perpetuity.
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