Author: Kumar, Satyendra; Arankalle, Vidya A.
Title: Intracranial Administration of P Gene siRNA Protects Mice from Lethal Chandipura Virus Encephalitis Document date: 2010_1_7
ID: 1mzq227n_46
Snippet: Histopathology of the brains of ncsiRNA treated mice showed typical features of viral encephalitis, such as meningeal vessels with perivascular cuffing of lymphocytes (Fig 9a) and focus of gliosis & demyelination in cortex (Fig 9b) . Absence of brain inflammation or neuropathology was obvious in P-2 siRNA-treated mice (Fig 9c and 9d ). Both mice groups were sacrificed on 5 th day post-CHPV inoculation......
Document: Histopathology of the brains of ncsiRNA treated mice showed typical features of viral encephalitis, such as meningeal vessels with perivascular cuffing of lymphocytes (Fig 9a) and focus of gliosis & demyelination in cortex (Fig 9b) . Absence of brain inflammation or neuropathology was obvious in P-2 siRNA-treated mice (Fig 9c and 9d ). Both mice groups were sacrificed on 5 th day post-CHPV inoculation.
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