Author: Jordana-Lluch, Elena; Giménez, Montserrat; Quesada, M. Dolores; Ausina, Vicente; Martró, Elisa
Title: Improving the Diagnosis of Bloodstream Infections: PCR Coupled with Mass Spectrometry Document date: 2014_4_9
ID: 05zahl5n_20
Snippet: Mass spectrometry is highly sensitive and can detect small amounts of a nucleic acid of a given sequence even in a complex mixture. The PCR/ESI-MS system employs a software algorithm that calculates a base composition for each amplicon based on mass, compares these to an extensive database, and achieves the identification of the pathogen [17, 31] ......
Document: Mass spectrometry is highly sensitive and can detect small amounts of a nucleic acid of a given sequence even in a complex mixture. The PCR/ESI-MS system employs a software algorithm that calculates a base composition for each amplicon based on mass, compares these to an extensive database, and achieves the identification of the pathogen [17, 31] .
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