Author: Brandon Malone; Boris Simovski; Clement Moline; Jun Cheng; Marius Gheorghe; Hugues Fontenelle; Ioannis Vardaxis; Simen Tennoe; Jenny-Ann Malmberg; Richard Stratford; Trevor Clancy
Title: Artificial intelligence predicts the immunogenic landscape of SARS-CoV-2: toward universal blueprints for vaccine designs Document date: 2020_4_21
ID: cm30gyd8_87
Snippet: The median conservation score was calculated by sampling 1,000 sub-sequences equal to the hotspot size from the entire consensus sequence of a protein. Each sample was assigned a conservation score and the median value from all 1,000 conservation scores was calculated. The minimum conservation score was calculated using a sliding window approach, with the window size being equal to the hotspot size. For each increment, a conservation score was ca.....
Document: The median conservation score was calculated by sampling 1,000 sub-sequences equal to the hotspot size from the entire consensus sequence of a protein. Each sample was assigned a conservation score and the median value from all 1,000 conservation scores was calculated. The minimum conservation score was calculated using a sliding window approach, with the window size being equal to the hotspot size. For each increment, a conservation score was calculated and the resulting minimum conservation score was kept.
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