Author: Leclercq, Loïc
Title: Interactions between cyclodextrins and cellular components: Towards greener medical applications? Document date: 2016_12_7
ID: 16pzlvzz_71
Snippet: Another common viral disease is caused by herpes simplex virus (HSV) leading to several distinct medical disorders including orofacial and genital herpes or encephalitis [157] . In this context, the anti-HSV properties of native CDs (α-and β-CD) have been estimated against HSV-1 and HSV-2 [158] . The antiviral properties were clearly dependent on the cavity size: α-CD exhibited no significant antiherpetic activity, while, under similar conditi.....
Document: Another common viral disease is caused by herpes simplex virus (HSV) leading to several distinct medical disorders including orofacial and genital herpes or encephalitis [157] . In this context, the anti-HSV properties of native CDs (α-and β-CD) have been estimated against HSV-1 and HSV-2 [158] . The antiviral properties were clearly dependent on the cavity size: α-CD exhibited no significant antiherpetic activity, while, under similar conditions, β-CD reduced both the cell-free and cell-associated virus more effectively than acyclovir (i.e., antiherpetic drug). Indeed, the results reveal an almost complete protection of Vero cells against acyclovir-sensitive and acyclovir-resistant strains of HSV. The ability of β-CD to impede virus replication is proposed as antiviral mechanism.
Search related documents:
Co phrase search for related documents- antiherpetic activity and HSV simplex virus: 1, 2, 3
- antiherpetic activity and significant antiherpetic activity: 1
- antiherpetic activity and simplex virus: 1, 2, 3, 4
- antiherpetic drug and herpes HSV simplex virus: 1
- antiherpetic drug and HSV simplex virus: 1
- antiherpetic drug and significant antiherpetic activity: 1
- antiherpetic drug and simplex virus: 1, 2
- antiviral mechanism and complete protection: 1, 2
- antiviral mechanism and herpes HSV simplex virus: 1, 2, 3, 4, 5, 6, 7, 8, 9
- antiviral mechanism and HSV simplex virus: 1, 2, 3, 4, 5, 6, 7, 8, 9
- antiviral mechanism and simplex virus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15
- antiviral mechanism and Vero cell: 1, 2
- antiviral mechanism and viral disease: 1, 2, 3, 4, 5
- antiviral mechanism and virus replication: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60
- antiviral mechanism propose and viral disease: 1
- antiviral mechanism propose and virus replication: 1
- antiviral property and herpes HSV simplex virus: 1, 2
- antiviral property and HSV simplex virus: 1, 2
- antiviral property and simplex virus: 1, 2, 3, 4
Co phrase search for related documents, hyperlinks ordered by date