Selected article for: "EBOV GP rvsv infection and GP rvsv"
Author: Rhein, Bethany A.; Powers, Linda S.; Rogers, Kai; Anantpadma, Manu; Singh, Brajesh K.; Sakurai, Yasuteru; Bair, Thomas; Miller-Hunt, Catherine; Sinn, Patrick; Davey, Robert A.; Monick, Martha M.; Maury, Wendy
Title: Interferon-? Inhibits Ebola Virus Infection
  • Document date: 2015_11_12
    • ID: 10bu7iwg_24
    Snippet: Previous studies have demonstrated that IFNγ treatment administered by intramuscular (i.m.) injection allows for slower release and an extended half-life of the drug [46] . Further, this injection route is utilized in many clinical therapeutics. Thus, we investigated the ability of this administration route to protect mice against lethal EBOV GP/rVSV. Mice given 10 μg of IFNγ by i.m. injection 24 hours prior to EBOV GP/rVSV infection significa.....
    Document: Previous studies have demonstrated that IFNγ treatment administered by intramuscular (i.m.) injection allows for slower release and an extended half-life of the drug [46] . Further, this injection route is utilized in many clinical therapeutics. Thus, we investigated the ability of this administration route to protect mice against lethal EBOV GP/rVSV. Mice given 10 μg of IFNγ by i.m. injection 24 hours prior to EBOV GP/rVSV infection significantly protected against lethal challenge (Fig 5D) .

    Search related documents:
    Co phrase search for related documents
    • administration route and injection route: 1, 2, 3, 4, 5, 6, 7, 8, 9
    • administration route and intramuscular injection: 1, 2, 3, 4, 5, 6, 7
    • administration route and lethal challenge: 1, 2, 3, 4, 5, 6
    • clinical therapeutic and drug life: 1
    • clinical therapeutic and half drug life: 1
    • drug life and half drug life: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • EBOV GP rvsv and GP rvsv: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • EBOV GP rvsv and GP rvsv infection: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21
    • EBOV GP rvsv and IFNγ 10 μg: 1, 2, 3
    • EBOV GP rvsv and IFNγ treatment: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12
    • EBOV GP rvsv and lethal challenge: 1, 2, 3, 4, 5
    • EBOV GP rvsv and lethal challenge protect: 1, 2, 3
    • GP rvsv and IFNγ 10 μg: 1, 2, 3
    • GP rvsv and IFNγ treatment: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12
    • GP rvsv and lethal challenge: 1, 2, 3, 4, 5
    • GP rvsv and lethal challenge protect: 1, 2, 3
    • GP rvsv infection and IFNγ 10 μg: 1, 2, 3
    • GP rvsv infection and IFNγ treatment: 1, 2, 3, 4, 5, 6, 7
    • GP rvsv infection and lethal challenge: 1, 2